Official Answer Key & Detailed Solution
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Correct Answer: Option (A) — O, Rh–
Concept & Option Breakdown
Standard Reference Verified• Option (a) is correct: O, Rh-negative (O, Rh–) red blood cells lack A, B, and Rh (D) surface antigens. As a result, transfusing O, Rh– blood into any recipient minimizes the risk of recipient antibody-mediated agglutination and hemolysis, making it the true universal donor.
Universal Red Blood Cell Donor = O negative (no antigens to trigger recipient antibodies). Universal Plasma Donor = AB positive.
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