Official Answer Key & Detailed Solution
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Correct Answer: Option (C) — Both 1 and 2
Concept & Option Breakdown
Standard Reference VerifiedStatement 1 is correct: Mitochondrial Replacement Therapy (MRT) can prevent transmission of mitochondrial diseases using techniques like Spindle Transfer (before fertilization) or Pronuclear Transfer (after in vitro fertilization). Statement 2 is correct: Mitochondrial DNA (mtDNA) is inherited strictly maternally because sperm mitochondria are degraded post-fertilization, meaning mitochondrial genetic disorders are passed exclusively from mothers.
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