Official Answer Key & Detailed Solution
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Correct Answer: Option (C) — Both 1 and 2
Concept & Option Breakdown
Standard Reference VerifiedStatement 1 is correct: When acidic chyme containing HCl enters the duodenum, the drop in pH stimulates duodenal S-cells to secrete the hormone secretin, which triggers the pancreas to release bicarbonate-rich fluid to neutralize acidity. Statement 2 is correct: Enterogastrone (a family of gastrointestinal hormones including CCK and GIP) is secreted by the duodenal mucosa in response to the presence of fats/fatty acids, inhibiting gastric motility and gastric acid secretion to slow digestion.
Both statements describe standard endocrine feedback mechanisms regulating digestive enzymes and motility in the duodenum.
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