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Question No. 10Interactive Test Mode
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Q10. ‘RNA interference (RNAi)’ technology has gained popularity in the last few years. Why? 1. It is used in developing gene-silencing therapies. 2. It can be used in developing therapies for the treatment of cancer. 3. It can be used to develop hormone replacement therapies. 4. It can be used to produce crop plants that are resistant to viral pathogens. Select the correct answer using the code given below.

‘RNA interference (RNAi)’ technology has gained popularity in the last few years. Why?

  1. It is used in developing gene-silencing therapies.
  2. It can be used in developing therapies for the treatment of cancer.
  3. It can be used to develop hormone replacement therapies.
  4. It can be used to produce crop plants that are resistant to viral pathogens. Select the correct answer using the code given below.
Select the correct option below (or cross out options to eliminate)

Official Answer Key & Detailed Solution

Ready to check the official UPSC Answer Key?

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Official UPSC Answer KeyUPSC Prelims 2019 • Science and Technology

Correct Answer: Option (A) — 1, 2 and 4

Concept & Option Breakdown

Standard Reference Verified

Statement 1 is correct: RNA interference (RNAi) uses small double-stranded RNA molecules (like siRNA or miRNA) to degrade target mRNA transcripts, thereby silencing specific gene expression. Statement 2 is correct: RNAi can target and downregulate oncogenes and genes responsible for tumor cell proliferation, drug resistance, and metastasis. Statement 3 is incorrect: Hormone Replacement Therapy (HRT) involves supplementing deficient hormones directly, not suppressing gene expression via RNAi. Statement 4 is correct: RNAi is widely deployed in plant biotechnology to silence viral genes or host susceptibility factors, conferring viral resistance in crops (e.g., transgenic papaya against ringspot virus).

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Question Specifications & Syllabus Mapping

Examination & YearUPSC Civil Services Preliminary Examination 2019 (Q10)
Paper & Marking SchemeGS Paper I • 2 Marks (-0.66 Negative for incorrect response)
Syllabus Subject & TopicScience and Technology → Biotechnology & Genetics
Official Answer KeyOption (A) — 1, 2 and 4

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Frequently Asked Questions — UPSC Prelims 2019 Q10

What is the official answer for UPSC Prelims 2019 GS Paper I Question 10 (Science and Technology)?

The official UPSC answer key for this 2019 Science and Technology (Biotechnology & Genetics) question is Option (A): "1, 2 and 4". Correct attempts carry 2 Marks with -0.66 Negative penalty for wrong answers.

Which UPSC Prelims syllabus topic does this 2019 question belong to?

This question belongs to GS Paper I under the subject "Science and Technology" and micro-topic "Biotechnology & Genetics". You can explore all repeated questions from Biotechnology & Genetics in Acme AI's 3D Prelims PYQ Realm or practice 50 full-length and sectional tests in the APT Prelims Test Series.

How can I solve this Biotechnology & Genetics UPSC Prelims question using option elimination?

To solve Biotechnology & Genetics questions in UPSC Prelims, identify extreme modifiers, verify core NCERT conceptual definitions, and eliminate mutually contradictory statement pairs before locking your final option.

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